The pKa's for carbonic acid and bicarbonate at 37°C are 3.83 and 10.25, respectively.Write the equation for each of these equilibria.
Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article.
![Acid Acid](/uploads/1/2/5/5/125507727/619244900.jpg)
Find more information on. Carbonic, lactic, and pyruvic acids have been generated in aqueous solution by the transient protonation of their corresponding conjugate bases by a tailor-made photoacid, the 6-hydroxy-1-sulfonate pyrene sodium salt molecule. A particular goal is to establish the p K a of carbonic acid H 2CO 3.
The on-contact proton transfer (PT) reaction rate from the optically excited photoacid to the carboxylic bases was derived, with unprecedented precision, from time-correlated single-photon-counting measurements of the fluorescence lifetime of the photoacid in the presence of the proton acceptors. The time-dependent diffusion-assisted PT rate was analyzed using the Szabo–Collins–Kimball equation with a radiation boundary condition. The on-contact PT rates were found to follow the acidity order of the carboxylic acids: the stronger was the acid, the slower was the PT reaction to its conjugate base. The p K a of carbonic acid was found to be 3.49 ± 0.05 using both the Marcus and Kiefer–Hynes free energy correlations.
This establishes H 2CO 3 as being 0.37 p K a units stronger and about 1 p K a unit weaker, respectively, than the physiologically important lactic and pyruvic acids. The considerable acid strength of intact carbonic acid indicates that it is an important protonation agent under physiological conditions.
Carbonic acid (YMDB00382) IdentificationYMDB IDYMDB00382NameCarbonic acidSpeciesSaccharomyces cerevisiaeStrainBaker's yeastDescriptionHydrogen carbonate, also known as bisodium carbonate or sal soda, belongs to the class of organic compounds known as organic carbonic acids. Organic carbonic acids are compounds comprising the carbonic acid functional group. Hydrogen carbonate is a very weakly acidic compound (based on its pKa).
Hydrogen carbonate exists in all living species, ranging from bacteria to humans.Structure. General function: Involved in acetyl-CoA carboxylase activity Specific function: Catalyzes the rate-limiting reaction in the mitochondrial fatty acid synthesis (FAS) type II pathway. Responsible for the production of the mitochondrial malonyl-CoA, used for the biosynthesis of the cofactor lipoic acid. This protein carries three functions:biotin carboxyl carrier protein, biotin carboxylase, and carboxyltransferase Gene Name: HFA1 Uniprot ID: Molecular weight: 259161.0 ReactionsATP + acetyl-CoA + HCO(3)(-) → ADP + phosphate + malonyl-CoA.ATP + biotin-carboxyl-carrier-protein + CO(2) → ADP + phosphate + carboxy-biotin-carboxyl-carrier-protein. General function: Involved in carbonate dehydratase activity Specific function: Catalyzes the reversible hydration of CO(2) to H(2)CO(3).
The main role may be to provide inorganic carbon for the bicarbonate-dependent carboxylation reactions catalyzed by pyruvate carboxylase, acetyl-CoA carboxylase and carbamoyl- phosphate synthetase. Involved in protection against oxidative damage. Encodes a substrate for the non-classical protein export pathway for proteins that lack a cleavable signal sequence Gene Name: NCE103 Uniprot ID: Molecular weight: 24859.0 Reactions H(2)CO(3) → CO(2) + H(2)O.